ADC Therapeutics (NYSE:ADCT – Get Free Report) issued its quarterly earnings data on Thursday. The company reported ($0.11) earnings per share (EPS) for the quarter, topping the consensus estimate of ($0.22) by $0.11, FiscalAI reports. The firm had revenue of $19.25 million for the quarter, compared to analyst estimates of $18.89 million.
Here are the key takeaways from ADC Therapeutics’ conference call:
- FDA raised substantial benefit-risk concerns regarding the LOTIS-5 combination of ZYNLONTA and rituximab, leaving ADC Therapeutics assessing whether additional data, risk-management measures, or label changes can support a regulatory filing.
- LOTIS-7 enrollment reached 100 patients, and management described the ZYNLONTA-plus-glofitamab data submitted to ASH as potentially practice-changing, with plans to seek breakthrough designation and evaluate a Phase III trial.
- Management said the FDA’s LOTIS-5 concerns were specific to the combination trial and did not affect ZYNLONTA monotherapy, which the company expects to remain available under accelerated approval in third-line-plus DLBCL.
- Q2 ZYNLONTA revenue was broadly stable at $18.6 million, while adjusted operating expenses fell 22% year over year; the June reorganization is expected to generate approximately $10 million in annual savings and extend cash runway into at least 2028.
ADC Therapeutics Stock Down 4.3%
ADCT opened at $1.00 on Friday. The firm has a market cap of $127.83 million, a P/E ratio of -1.52 and a beta of 1.89. The business’s fifty day simple moving average is $1.15 and its 200 day simple moving average is $2.88. ADC Therapeutics has a 52 week low of $0.78 and a 52 week high of $4.98.
Institutional Inflows and Outflows
Analyst Upgrades and Downgrades
A number of brokerages have recently weighed in on ADCT. Wall Street Zen upgraded ADC Therapeutics from a “sell” rating to a “hold” rating in a research report on Saturday. Stephens reissued an “overweight” rating and issued a $5.00 price objective on shares of ADC Therapeutics in a research note on Thursday, June 4th. Cantor Fitzgerald restated an “overweight” rating on shares of ADC Therapeutics in a report on Thursday, June 4th. HC Wainwright cut shares of ADC Therapeutics from a “buy” rating to a “neutral” rating in a research report on Monday, June 8th. Finally, Weiss Ratings reiterated a “sell (d-)” rating on shares of ADC Therapeutics in a research report on Friday, July 17th. Three equities research analysts have rated the stock with a Buy rating, two have given a Hold rating and one has given a Sell rating to the company’s stock. According to data from MarketBeat, ADC Therapeutics currently has an average rating of “Hold” and an average price target of $6.25.
Read Our Latest Analysis on ADCT
ADC Therapeutics Company Profile
ADC Therapeutics SA is a clinical-stage biopharmaceutical company focused on the discovery and development of highly targeted antibody-drug conjugates (ADCs) designed to treat hematological malignancies such as non-Hodgkin lymphoma and acute myeloid leukemia. By marrying the specificity of monoclonal antibodies with potent cytotoxic payloads, the company aims to maximize tumor cell eradication while limiting off-target toxicity.
At the core of ADC Therapeutics’ portfolio is loncastuximab tesirine-lpyl, a CD19-directed ADC that received accelerated approval from the U.S.
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